Directed Evolution of Near-Infrared Serotonin Nanosensors with Machine Learning-Based Screening
In this study, we employed a novel approach to improve the serotonin-responsive ssDNA-wrapped single-walled carbon nanotube (ssDNA-SWCNT) nanosensors, combining directed evolution and machine learning-based prediction.Our iterative optimization process is aimed at the sensitivity and selectivity of ssDNA-SWCNT nanosensors.In the Caster Accessories